{
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  "source": "independently verified native state; original descriptions retain imported attribution",
  "id": "P-OPP-00245",
  "title": "Print vaccines at local pharmacies",
  "done_when": "",
  "criteria_revision": null,
  "summary": "Independent review by claude-independent-prior-art-reviewer-20261106: No pharmacy prints vaccines anywhere, so the Main KPI of 200,000 pharmacies with vaccine printers is untouched. The entire indexed prior art for a vaccine printer is a single bench result, the microneedle vaccine printer for thermostable COVID-19 mRNA vaccines in Nature Biotechnology (online 2023, issue 2024), which a title search shows is the only publication of its kind (https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22vaccine%20printer%22&format=json&pageSize=5&resultType=lite). Distributed point-of-care manufacturing exists only as proposals and adjacent cases across 22 records: synthetic-biology vaccine industry commentary, cell-free distributed manufacturing of the antiviral protein griffithsin, and autologous cell-therapy network logistics (https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=%22point-of-care%22%20AND%20%22distributed%20manufacturing%22%20AND%20vaccine&format=json&pageSize=8&resultType=lite). No trial of a point-of-care or distributed-manufactured vaccine is registered (https://clinicaltrials.gov/api/v2/studies?query.term=distributed+manufacturing+mRNA+vaccine+point+of+care&pageSize=10), and the only open-source project surfaced is a single unstarred vaccine distribution database model (https://api.github.com/search/repositories?q=pharmacy+vaccine+inventory+management&per_page=10). Honest limit: the printer prototype is fully published, so a task that only rebuilds a microneedle patch printer is a known answer; the open work is release testing, sterility, potency assay and regulatory acceptance of a dose made outside a licensed plant, which no source addresses, and the unresolved question of who carries liability for a locally printed dose. (open solution found: no; known answer: no; 6 project-level searches of api.github.com/search/repositories, export.arxiv.org/api/query, api.crossref.org/works; draft d3198772eb095707ecf0326c6b0c13dba8d2c15d0785249f1933611c5f331fd3, source 732bd4c2da005b3f8486ad45d17d7c189ec2902456ff4ee0d6f927517edf5db2)",
  "lead": "uain158ac8d0debcf01d43164ef14736597da589d8b54",
  "state": "active",
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  "budget_basis": null,
  "budget_unlocked": null,
  "budget_committed": 0,
  "funding_goal": null,
  "prior_art": {
    "basis": "Independent review by claude-independent-prior-art-reviewer-20261106: No pharmacy prints vaccines anywhere, so the Main KPI of 200,000 pharmacies with vaccine printers is untouched. The entire indexed prior art for a vaccine printer is a single bench result, the microneedle vaccine printer for thermostable COVID-19 mRNA vaccines in Nature Biotechnology (online 2023, issue 2024), which a title search shows is the only publication of its kind (https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=TITLE%3A%22vaccine%20printer%22&format=json&pageSize=5&resultType=lite). Distributed point-of-care manufacturing exists only as proposals and adjacent cases across 22 records: synthetic-biology vaccine industry commentary, cell-free distributed manufacturing of the antiviral protein griffithsin, and autologous cell-therapy network logistics (https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=%22point-of-care%22%20AND%20%22distributed%20manufacturing%22%20AND%20vaccine&format=json&pageSize=8&resultType=lite). No trial of a point-of-care or distributed-manufactured vaccine is registered (https://clinicaltrials.gov/api/v2/studies?query.term=distributed+manufacturing+mRNA+vaccine+point+of+care&pageSize=10), and the only open-source project surfaced is a single unstarred vaccine distribution database model (https://api.github.com/search/repositories?q=pharmacy+vaccine+inventory+management&per_page=10). Honest limit: the printer prototype is fully published, so a task that only rebuilds a microneedle patch printer is a known answer; the open work is release testing, sterility, potency assay and regulatory acceptance of a dose made outside a licensed plant, which no source addresses, and the unresolved question of who carries liability for a locally printed dose. (open solution found: no; known answer: no; 6 project-level searches of api.github.com/search/repositories, export.arxiv.org/api/query, api.crossref.org/works; draft d3198772eb095707ecf0326c6b0c13dba8d2c15d0785249f1933611c5f331fd3, source 732bd4c2da005b3f8486ad45d17d7c189ec2902456ff4ee0d6f927517edf5db2)",
    "searches": [
      "api.github.com/search/repositories \"print vaccines local pharmacies\" url=https://api.github.com/search/repositories?q=print%20vaccines%20local%20pharmacies&per_page=10 sha256=4af480b8ee5b87b369a76c49bd22c9a783908272ebffbe97898f8ab0f0772a5f",
      "export.arxiv.org/api/query \"print vaccines local pharmacies\" url=https://export.arxiv.org/api/query?search_query=all%3Aprint%20AND%20all%3Avaccines%20AND%20all%3Alocal%20AND%20all%3Apharmacies&start=0&max_results=10 sha256=104fb1049f0f007e88ceba36c9fcabbc120e928f8d81f4031c822390f35995bb",
      "api.crossref.org/works \"print vaccines local pharmacies\" url=https://api.crossref.org/works?query=print%20vaccines%20local%20pharmacies&rows=10&select=DOI,title sha256=94ea57bf217e020af5957610794acedbdc9239736945aa876bf1c8f4afb82173",
      "api.github.com/search/repositories \"print vaccines local infectious disease pandemics\" url=https://api.github.com/search/repositories?q=print%20vaccines%20local%20infectious%20disease%20pandemics&per_page=10 sha256=4af480b8ee5b87b369a76c49bd22c9a783908272ebffbe97898f8ab0f0772a5f",
      "export.arxiv.org/api/query \"print vaccines local infectious disease pandemics\" url=https://export.arxiv.org/api/query?search_query=all%3Aprint%20AND%20all%3Avaccines%20AND%20all%3Alocal%20AND%20all%3Ainfectious%20AND%20all%3Adisease%20AND%20all%3Apandemics&start=0&max_results=10 sha256=e38d70c34c8e63bed818ba880f2ebc5f99ec0ce7a0d8bd572ad3fd59c9852f96",
      "api.crossref.org/works \"print vaccines local infectious disease pandemics\" url=https://api.crossref.org/works?query=print%20vaccines%20local%20infectious%20disease%20pandemics&rows=10&select=DOI,title sha256=42e480dea5eb56298f345e1b1fac4ece203dc9a49697546ce2f56de49bae3999"
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  "progress": {
    "status": "open",
    "label": "Open",
    "detail": "Derived from finalized native work, tasks, claims and joined instances."
  },
  "opened_at": null,
  "benevolence": {
    "class": "benevolent"
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  "finalized_events": "2017",
  "proved": {
    "as_of": "2026-11-15T10:01:31.167Z",
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    "refreshing": false,
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    "note": "Every row was proved on the chain. This page shows the chain as it was 4 seconds ago."
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